Dergiler / Turkish Journal of Mathematics / 2010 / Cilt: 34 - Sayı: 3

On the Qualitative Analysis of the Uniqueness of the Movement of Endothelial Cells

Sayfa
367–375
DOI
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Özet

This paper extends the work of Pamuk (2003) by showing mathematically that the movement of endothelial cells, to the regions where active enzyme is large or where fibronectin is small, is unique. To do this, we obtain the existence and uniqueness of the steady-state solution of an initial-boundary value problem which mathematically models endothelial cell movement in tumor angiogenesis. A specific example showing the instability of this steady-state solution is provided.

Abstract

This paper extends the work of Pamuk (2003) by showing mathematically that the movement of endothelial cells, to the regions where active enzyme is large or where fibronectin is small, is unique. To do this, we obtain the existence and uniqueness of the steady-state solution of an initial-boundary value problem which mathematically models endothelial cell movement in tumor angiogenesis. A specific example showing the instability of this steady-state solution is provided.

Anahtar kelimeler: Existence; uniqueness; tumor angiogenesis; steady-state solution; transition probability density function.