Potentiometric and spectroscopic determination of acid dissociation constants of some phenols and salicylic acids

Abstract

The dissociation constant of the catechol derivatives 4-nitrocatechol (NCAT), 2,3-dihydroxybenzoic acid (2,3-DHBA), 3,4-dihydroxybenzoic acid (3,4-DBHA), 3,4-dihydroxyhenylacetic acid (3,4-DPHA) and 3,4-dihydroxycinnamic acid (3,4-DHCA) were identified in 0.1M 4NaClO_4$ ionic medium, at $t=25^circ C$, by potentiometry. In addition, the first and second dissociation constants of the salicylic acid derivatives 5-nitrosalicylic acid (5-NSA), 4-hydroxysalicylic acid (4-HSA) 5-nitrosalicylic acid (5-HSA) were also determined by potentiometry. Furthermore, the second acid dissociation constants of these ligands were evaluated in I=0.1M $NaClO_4 ionic medium, at a temperature of $25^circ C$ by computer analysis of spectroscopic data.