Spectroscopic characterization and biological applications of organotin (IV) derivatives of 3-(N-naphthylaminocarbonyl)-2-propenoic acid

Abstract

In an effort to develop new organotin materials for investigation and biocidal evaluation, a series of compounds with the general formula $R_{4_n}SnL_n$ (where R = $CH_3$, $n-C_4H_9$, $C_6H_5$, $C_6H_5CH_2$ and L = 3-(N-naphthylaminocarbonyl)-2-propenoic acid) were synthesised, and characterised by elemental analysis, IR, multinuclear ($^1H$, $^{13}C$ and $^{119 }Sn$) NMR, $^{119m}Sn$ Mössbauer spectroscopy and mass spectrometry. The biological activity of these compounds against various bacteria and fungi was investigated. All of the compounds were active against the fungi tested with a few exceptions. These compounds also showed significant antibacterial activity. $LD_{50}$ data show that the investigated compounds have significant toxicity.