One-pot synthesis of substituted 4H -chromenes by nickel ferrite nanoparticles as an efficient and magnetically reusable catalyst

Abstract

Nickel ferrite magnetic nanoparticles (NiFe 2 O4 MNPs) were prepared via the autocombustion assisted solgel method. The efficient catalyst was investigated by FT-IR, XRD, ICP, SEM, and TEM techniques. A one-pot,three-component reaction is reported for the synthesis of substituted 4H -chromenes in the presence of NiFe 2 O4 MNPsas a reusable catalyst in a green solvent at 40 ◦ C under clean, efficient, and mild conditions. Furthermore, selectedproducts were characterized by FT-IR, 1 H NMR, and 13 C NMR. The single-crystal X-ray analysis of product 4uwas also conclusively confirmed. Easy workup procedure, high purity of products via simple recrystallization, andenvironmentally benign conditions are the outstanding benefits of this method.