Beta endorphins - molecules of therapeutics

Abstract

Endorphins are endogenous morphine, neuropeptides produced in the pituitary gland. There are three types ofendorphins beta-endorphins, enkephalins, and dynorphins. Beta-endorphins are an abundant endorphinssynthesized and stored in the anterior pituitary gland; it is a precursor of POMC (Proopiomelanocortin). Betaendorphins has got various mechanisms of actions such as anti-inflammatory activity, analgesic activity, stressbuster activity, and immune stimulatory activity can be used to treat various diseases such as chronicinflammatory diseases such as heart disease, Alzheimer’s disease, cancer, auto-immune disease, diabetesmellitus, and aging. This article highlights about the basic research findings of beta-endorphins and mechanismsof actions in management of various diseases