The association between lipid profile and bone mineral density in subjects with ankylosing spondylitis

Abstract

Objective: This study aims to investigate the relationship between serum lipids and bone mineral density inankylosing spondylitis patients.Methods: A total of 94 ankylosing spondylitis patients fulfilling the 1984 Modified New York Criteria whohad serum lipid levels and bone mineral density scores in medical records were included in this study. Thesepatients treated with nonsteroid antiinflammatory drugs. Their files were examined in detail. Later demographicand laboratory features were recorded to the research form. Dual-energy X-ray absorptiometry was used toassess bone mineral density in two bone sites of femur (neck, intertrochanteric zone and trochanter) and spinallumbar vertebras (Lumbar 1-Lumbar 4).Results: Significant and positive correlation was found between high density lipoprotein and femoral neckbone mineral density (r = 0.356, p = 0.021) in osteopenic group and in osteoporotic group (r = 0.005, p =0.040).Conclusion: According to our study significant and positive correlations are found between high densitylipoprotein and femoral neck bone mineral density in osteopenic and osteoporotic group. However, we believethat more studies are needed about this research.