A new etiology for variant of Guillain-Barré syndrome: bariatric surgery

Abstract

Bariatric surgery is an effective treatment for obesity. However, the number of acute or chronic neurologicalcomplications after bariatric surgery, including Guillain-Barré syndrome, is increasingly reported. We presenthere two cases which developed acute motor sensory polyneuropathy a couple months after bariatric surgerywhich rapidly progressed over the following month. Both patients used received parenteral vitamin B complexreplacement after surgery. The first case responded well to intravenous immunoglobulin (IVIg) treatment.However, the second case required plasmapheresis and physical rehabilitation for recovery after IVIg treatment.It is thought that minerals, vitamins, and trace element deficiencies can develop after bariatric surgery. Thesedeficiencies may trigger inflammatory and autoimmune mechanisms and cause acute polyneuropathies. In suchcases, it should be kept in mind that immune therapies may be beneficial, as well as vitamins.