Intratunical instillation of bupivacaine and methylprednisolone for relief of scrotal pain and swelling from TESE or MESA

Abstract

Objective: Scrotal pain and swelling due to surgical sperm retrieval procedures and peritesticular fibrosis, as a problem of late term, create significant morbidity in the postoperative life of patients and affect possible future sperm retrieval procedures. Methods: Thirty-one patients received NSAIDS postoperatively by IM (intramuscular) route without local anaesthetic agent and/or corticosteroid instillation around the testicles before closure of the tunica vaginalis-control group-. No NSAIDS were given to the remaining 34 patients in whom 2.5 ml of 0.5% bupivacaine combined with 10 mg/ml. Methylprednisolone were introduced before closing of the tunica vaginalis. The mean pain scale scores and duration of painless period after surgery between the two groups were evaluated. Results: The mean pain score difference was not statistically significant just after surgery between the two groups (p>0.05), while the differences were significant for 2 and 4 hours after surgery (p