Oral Mukozal Lezyonlara Ait Histopatolojik Sonuçların Retrospektif Analizi

Özet

Amaç: Oral mukozal lezyonun morfolojik ozelliklerine go ̈ re ya- ̈ pılan ilk degerlendirme bize tan ̆ ı ve takip acı̧sından onemli bilgi ver- ̈ mektedir, bununla birlikte kesin tanı alınan biyopsi sonrasında yapılan histopatolojik inceleme sonucu konabilmektedir. Bu cal ̧ ısmada, oral mu- ̧ kozal lezyon nedeniyle biyopsi alınan hastaların histopatolojik tanıları degerlendirildi. ̆ Gerec ve Yo ̧ ntemler: ̈ 2009 ve 2016 yılları arasında oral mukozadan oral mukozal lezyon nedeniyle biyopsi alınan hastaların histopatoloji sonuclar ̧ ı tanıların gorü lme s ̈ ıklıgı̆na, lokalizasyonuna, yaş ve cinsiyet dagı̆lımlarına gore deg ̈ erlendirildi. Lezyonlar ayr ̆ ıca benign nonneoplazik, benign neoplazik, premalign ve malign lezyon olma ozelliklerine go ̈ re grupland ̈ ırılarak her grup icin veriler incelendi. ̧ Bulgular: Uc̈ yu ̧ z k ̈ ırk hastanın 193’u (%56,8) kad ̈ ın, 147’si (%43,2) erkekti. Histopatolojik tanılar gruplara göre değerlendirildiğinde 177 (%52,1) hastada benign nonneoplazik lezyon, 126 (%37,1) hastada benign neoplazik lezyon, 14 (%4,1) hastada premalign lezyon ve 23 (%6,8) hastada malign lezyon izlendi. Malign lezyonların buyü k c ̈ oģ unlug ̆ unu ̆ skuamoz hu ̈ creli karsinom olus ̈ turmaktayd ̧ ı. Premalign ve malign lezyonlarda yas ortalamas ̧ ı, benign lezyonlara sahip hastaların yas ortala- ̧ masına gore anlaml ̈ ı derecede yuksek bulundu (p

Abstract

Objective: The first evaluation according to the morphological features of the oral mucosal lesion gives us important information in terms of diagnosis and follow-up, however, the accurate diagnosis can be made after histopathological examination. In this study, the histopathological diagnoses of patients who underwent biopsy for oral mucosal lesions were evaluated. Material and Methods: The histopathological results of patients who underwent oral mucosal biopsies between 2009 and 2016 were evaluated according to the frequency of occurrence, localization, age and gender distribution of the diagnoses. Lesions were also grouped according to their characteristics of being benign non-neoplastic, benign neoplastic, premalignant, and malignant, and data were analyzed within groups. Results: Of the 340 patients, 193 (56.8%) were female and 147 (43.2%) were male. When the histopathological diagnoses were evaluated according to the groups, 177 (52.1%) patients had benign non-neoplastic, 126 (37.1%) patients had benign neoplastic, 14 (4.1%) patients had premalignant, and 23 (6.8%) patients had malignant lesions. Most of the malignant lesions were squamous cell carcinoma. The mean age of premalignant and malignant lesions was found to be significantly higher than the mean age of patients with benign lesions (p