Spectrophotometric Determination of Sunset Yellow (E-110) in Powdered Beverages and Pharmaceutical Preparations after Cloud Point Extraction Method

Abstract

In this study, Brij 58 was used for the spectrophotometric determination of sunsetyellow (SY) (E-110) in pharmaceutical preparations and powdered beverages after cloud pointextraction (CPE). Certain parameters such as pH, surfactant concentration, extraction time andtemperature, speed of centrifugation, and salt concentration were optimized. Linear range in theoptimum conditions was 0.01 – 4.00g mL-1 and the correlation coefficient was 0.9995. Thelimit of detection (LOD) and the limit of quantification (LOQ) of this method were 0.0078g mL-1 and 0.0261 g mL-1, respectively.