Dergiler / Journal of the Turkish Chemical Society, Section A: Chemistry / 2018 / Cilt: 5 - Sayı: 1
Boronic acid-functionalized silica microparticles for isolation of flavonoids from Hypericum perforatum
- Sayfa
- 41–60
- DOI
- —
Abstract
We have selectively separated cis- and/or vicinal-diol-containing flavonoids fromHypericum perforatum (HP) by adsorption/desorption used aminophenylboronic acid (APBA)functionalized uniform (1.6 μm) silica microparticles (BASPs) synthesized via the Stöber method.Silica particles were alkylated via its terminal –OH by 3-aminopropyl trimethoxysilane (APTS),glutaraldehyde (GA) and APBA. The results from model adsorption studies were indicated thatthese microparticles selectively had adsorbed quercetin and rutin but partially apigenin. Theantioxidant and antiradical activities of the desorption solution were slightly higher than the postadsorptionsolution. These results indicated that the BASP selectively adsorbed the cis- and/orvicinal antioxidant and antiradical flavonoids.