Is mean platelet volume better than other long-used noninvasive parameters in assessing severe fibrosis in patients with chronic hepatitis B?

Abstract

Aim: This study was aimed at i-) investigating the correlation between the severity of hepatic fibrosis and mean platelet volume(MPV) ii-) comparing the accuracy rate of MPV with that of other long-used non-invasive parameters in predicting severehepatic fibrosis in patients with chronic hepatitis B (CHB).Material and Method: Ninety-nine patients with CHB were enrolled. The patients were assigned to two groups, based on theirhepatic fibrosis scores. Those with scores ranging from 0 to 3 (mild to moderate fibrosis) were assigned to Group 1, and thosewith scores ranging from 4 to 6 (severe fibrosis) were included in Group 2.Results: The mean age of the patients was 42±13, and 69 (70%) of them were male. Twenty two patients (22%) were in Group2. Patients in Group 2 displayed significantly lower albumin and platelet count (p