Prematüre olguların okul çocukluğu dönemindeki akciğer fonksiyon testleri ve bronş hiperreaktivitesi

Lung function tests and bronchial hyperreactivity of premature cases at the school age

Özet

Bu çalışma prematüre doğum öyküsü olan çocukların uzun süreli akciğer sekellerini belirlemek ve bronşial hiperreaktivite varlığını saptamak, bunların nedenlerini araştırmak amacıyla planlanmıştır. Çalışma İstanbul Üniversitesi İstanbul Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Neonatoloji Bilim dalında 1985-1989 yılları arasında izlenen, doğum tartısı

Abstract

Lung function tests and bronchial hyperreactivity of premature cases at the school age. This study was planned with objective of determining long lasting lung sequela and existence of bronchial hyperreactivity in children with premature birth history and investigating their causes. The study was carried out at neonotology division of podiatry department at Istanbul University Medicine Faculty through observation of 27 premature case group with birth weight below 2000 grams and gestation age under 37 months between 1985 and 1989. The control group was composed of 24 healthy children at the ages ranging from 6 and 10 years old who were born mature. In order to determine bronchial hyperreactivity, lung function test with spirometer and exercise provocation test in the form of fast run for 6 minutes were applied to all cases. Neither neonatal respiration illness was observed nor respiration support was needed in any of the 27 premature case group. During our study, it was noted that while forced vital capacity of our premature cases was preserved, their forced expiratory flow indexes were found low. The FEF 25-75, FEF 25, FEF50, FEF 75 and PEF values of our premature cases were found to be significantly low compared to the control group (p