A Rare Skin Lesion Seen in Acute Myeloid Leukemia: Skin Infiltration

Özet

Yetişkinlerde görülen lösemilerin %80'ini akut myeloid lösemiler (AML) oluşturur. AML'de çok ve çeşitli dermatolojik bulgular olmasına rağmen bunlar çoğunlukla sitopenilere ve hemostaz bozukluklarına bağlı olup cilt tutulumu sık değildir. Leukemia cutis (LC) tanısı, sıklıkla sistemik lösemi ile eş zamanlı olarak veya sistemik lösemi tanısından sonra konur. Bu sunumda deri döküntüleri nedeniyle acil servise başvuran ve takipte akut myeloid lösemi tanısı alan bir olgu tartışılmıştır

Abstract

80% of leukemias in adults present as the acute myeloid leukemia (AML) form. Many different types of skin lesion can be seen in the course of leu- kemias. Most of them are benign lesions resulting from chemotherapeu- tic drug reactions, infectious complications due to immunosuppression, cytopenias or hemorrhagic diathesis. Leukemia cutis (LC) are rare lesions of the skin showing infiltration of malignant cells. The diagnosis of LC is often made with or after the diagnosis of systemic leukemia. In this study we discuss a patient who was admitted to the emergency department be- cause of skin rashes and was diagnosed with AML. LC was detected in this patient after a follow-up biopsy of skin lesions