Evaluation of Kidney Biopsies in Adults; 10 Years Single-Center Experience

Abstract

Introduction: Kidney biopsy is a frequent method of assessing the cause, extent and sometimes the appropriate treatment response of renal parenchymal diseases. In this study, we evaluated the clinicopathologic features of kidney biopsy exami- nations performed in our center for 10 years. Methods: A total of 532 native kidney biopsies performed in the adult age group between the years 2005-2014 in Hay- darpaşa Training and Research Hospital were evaluated retrospectively. All biopsy specimens were examined by light mi- croscopy and immunofluorescence by the same pathologist in the same laboratory. Results: The mean age of the cases was 41.3±12.8 years (18-65 years) and the percentage of males was 52.3% (n=278). The most frequent biopsy indication for primary and secondary glomerulonephritis was nephrotic-range proteinuria. The most frequent histopathologic diagnoses were focal segmental glomerulosclerosis among primary glomerulonephritis and dia- betic nephropathy among secondary glomerulonephritis. Discussion and Conclusion: As a result of the evaluation of 10-year kidney biopsy series at our center, results which are in general compatible with the national and international literature have been obtained. We concluded that establishment of kidney biopsy databases both at local centers and at national scales would be beneficial in the evaluation of kidney diseases.