The Triangle that can Improve Postmenopausal Women’s Quality of Life: Insulin, Bone Mineral Density, and Fracture Risk

Abstract

Introduction: Women spend most of their life in the postmenopausal period. This period brings along many metabolic problems with the decrease in estrogen production. Our aim was to evaluate the effectiveness of bone mineral density (BMD) on fracture risk assessment tool (FRAX) between groups with and without insulin resistance and also to investigate the importance of new risk factors in FRAX identification and to facilitate early prevention, diagnosis, and treatment of wom- en with fractures risk. Methods: Sixty-eight patients who were admitted to our clinic with diagnosis of impaired glucose tolerance during post- menopausal period were included in this study retrospectively. Those who had their routine biochemical parameters, insulin, and BMD measured were included in the study. Fracture risk analyses were performed with the FRAX score. Body mass index and homeostasis model assessment-insulin resistance of the patients were calculated. Results: In the group with insulin resistance, high-density lipoprotein cholesterol value was low (p=0.014), and triglyceride level was high (p