Dergiler / Harran Üniversitesi Tıp Fakültesi Dergisi / 2013 / Cilt: 10 - Sayı: 3
Effects of hemodialysis on the left and right heart functions in patients with end-stage renal disease
- Sayfa
- 114–123
- DOI
- —
Özet
Amaç: Kronik böbrek yetmezli ği olan hastalarda morbidite ve mortalite riskinin arttığı bilinmektedir.Kronik böbrek yetmezliği olan hastalarda hemodiyalizin sol ve sağ ventrikül sistolik ve diyastolikfonksiyonları üzerine etkisini konvansiyonel ve doku Doppler ekokardiyografi ile değerlendirmeyi amaçladık.Materyal ve metod: Bu ileriye dönük gözlemsel çalışmada hemodiyaliz öncesi ve diyalizden 60 dakikasonra 41 üremik hasta ekokardiyografi ile değerlendirildi. İki boyutlu, M- Mode, konvansiyonel ve dokuDoppler ekokardiyografi ile sol ve sağ ventrikülün sistolik ve diyastolik fonksiyonları ölçüldü.Bulgular: Hemodiyaliz sonrası kalp hızı anlamlı olarak artarken ortalama vücut ağırlığı, sistolik vediyastolik kan basınçları azaldı (hepsi için p
Abstract
Background: It is known that patients with chronic renal failure are at increased risk for morbidity andmortality. We aimed to assess the effects of hemodialysis on certain parameters used to evaluate left and rightventricular systolic and diastolic functions using conventional and tissue Doppler echocardiography inpatients with end-stage renal insufficiency.Methods: In this prospective observational study, 41 uremic patients were evaluated via echocardiographybefore and 60 minutes after hemodialysis. Systolic and diastolic functions of left ventricle (LV) and rightventricle (RV) were measured by two dimensional, M-Mode, conventional and tissue Dopplerechocardiography.Results: While a significant increase was observed in the mean heart rate after hemodialysis, the mean bodyweight, systolic and diastolic blood pressure values were significantly decreased (all p values< 0.01).Compared to before hemodialysis, mitral E/ mitral annulus septal E' and mitral E/ mitral annulus lateral E' didnot change (p= 0.105 and p= 0.165), but significant alterations were determined in many of M-Mode,conventional and other tissue Doppler echocardiographic parameters after hemodialysis (all p values< 0.05and < 0.01).Conclusions: Mitral E/ septal E' and mitral E/ lateral E' did not change following hemodialysis and thereforeare the best parameters to use to assess diastolic function in hemodialysis patients. Since the otherconventional and traditional Doppler parameters vary with hemodialysis, these are not accuratemeasurements in these patients.