Osteoporoz hastalarında kırığın yaşam kalitesine etkisi ve kırıkla ilişkili faktörler

Effect of fracture on quality of life in osteoporosis patients and factors related with fracture

Yasemin YUMUŞAKHUYLU, Afitap İÇAĞASIOĞLU, Raife Şirin ÇOBAN, Pınar AKPINAR, Hatice Şule BAKLACIOĞLU, Esra SELİMOĞLU, Selin TURGUT

Özet

Amaç: Osteoporoz (OP) hastalarında kırığın yaşam kalitesine etkisini, kırık ile ilişkili faktörleri araştırmak ve kırığı olmayan osteoporoz hastalarıyla karşılaştırmak. Gereç ve Yöntem: Çalışmaya Sağlık Bakanlığı Göztepe Eğitim ve Araştırma Hastanesi Fizik Tedavi ve Rehabilitasyon polikliniğine başvuran ve osteoporoz tanısı alan 106 kadın, 9 erkek toplam115 hasta alındı. Hastalar vertebra kırığı olan, kalça kırığı olan ve kırığı olmayan olmak üzere üç gruba ayrıldı. Hastalar sosyodemografik özellikler ve risk faktörlerini içeren soru formu ve Avrupa Osteoporoz Derneği Yaşam Kalitesi Anketi (QUALEFFO-41) yaşam kalitesi soru formlarını cevaplandırdı. Kemik mineral yoğunluğu (KMY) dual enerji x-ray absorbsiyometri (DEXA) ölçümüyle belirlendi. Vertebra kırığını belirlemek için Genant yöntemi kullanıldı. Hasta gruplarının risk faktörleri ve yaşam kalitesi skorları karşılaştırıldı. Bulgular: 115 hastanın yaş ortalaması 68.32±8.91 olup kırığı olmayan grubun yaş ortalaması diğer gruplardan anlamlı düşüktü (p0.05). kırığı olan grupların menopoz süresi daha uzundu (p

Abstract

Objective: The aims of this study were to asses the impact of fracture on quality of life in osteoporosis patients, factors related with fractures and compare them with osteoporosis patients without fracture. Material and Method: 115 (106 women, 9 men) osteoporosis patients who came to Ministry of Health Göztepe Education and Research Hospital Physical Medicine and Rehabilitation Department out-patient clinic were included in the study. Patients were divided into three groups as; vertebral fracture group, hip fracture group and no fracture group. Patients answered questions in forms that includes sociodemographic properties, risk factors, QUALEFFO-41 quality of life scale. Bone mineral density was measured by dual x-ray absorbsiometry and vertebral fractures were detected by Genant method. Results: Age of these 115 patients were changing between 49 and 90 with average of 68.32±8.91. Mean age of patients without fractre was significantly lower than other groups. There was no significant difference between groups about height, weight, body mass index, life style ( nutritional calcium intake, cigarette smoking, coffee and alcohol use, physical activity, sun exposure, wearing style), menopause age, menopause type, menarche age, familiy history of fracture, previous non vertebral and nonhip fractures but menopause duration was higher in patients with fracture. Parity of hip fracture group was lower than other groups. Risk factors related with falls were significantly higher in hip fracture group. Bone mineral density and T-scores of lomber region in vertebral fracture group were significantly lower than no fracture group and femur total BMD and T-scores of vertebra and hip fracture groups were significantly lower than no fracture group. QUALEFFO-41 pain, physical function, social function and total scores were significantly higher in vertebra and hip fracture groups meaning worse quality of life. Conclusions: It was detected that older age, long duration of menopause and lower BMD were related with fractures . Fractures decreases quality of life in osteoporosis patients. We think that detection of factors related with fractures in studies could achieve this personal, social and economic problem.