Can the Ratio of Calcium to Albumin Predict the Severity of Aortic Stenosis?

Abstract

Objective: Aortic sclerosis is observed in 25% of the elderly population, and 2.5% of these patients have severe aortic stenosis (AS). Numerous studies have reported a relationship between the serum calcium or albumin levels and AS. The present study investigated the relationship between the calcium toalbumin ratio (CAR) and AS. Methods: Our study included 185 patients and 108 subjects as the control group. A routine transthoracic echocardiographic evaluation and laboratory examinations were performed inall participants. The corrected serum calcium levels were calculated using the most commonly used formula: corrected calcium=measured total calcium (mg/dL) + 0.8 (4.0−serum albumin [g/dL]). Results: The serum C-reactive protein CRP, calcium, and corrected calcium levels were significantly different between the study groups (p