Primary Extranodal Non-Hodgkin’s Lymphoma of Maxillary Sinus: Rare Incident

Abstract

Non-Hodgkin lymphoma (NHL) commonly arises from lymphoid organ and tissues. But up to 35% of cases have beenreported to primarily originate from extranodal sites. Primary paranasal sinus lymphoma accounts for 8% of all paranasalmalignancies and a mere 2% of all primary extranodal lymphoma. We described a 72-year-old woman with primaryextranodal diffuse large B-cell lymphoma (DLBCL) originated from maxillary sinus extended into adjacent sinuses andstructures. She presented with painful, numb, vague, diffuse, hard swelling over right medial canthus since two months.There was no diplopia. She had right epiphora since two weeks. Minimal proptosis was seen in the right eye. There wasno history of foul smelling nasal discharge or obstruction. There was no neck swelling. She did not have underlyingcomorbid illnesses. Rigid nasal endoscopy revealed a friable mass arising from the right osteomeatal complex (OMC)occupying the entire right side of nasopharynx. Computed tomography (CT) revealed a soft tissue mass occupying theentire right maxillary sinus extending into adjacent structures. Treatment was completed and patient remained in remission. Features pertaining to demographic, markers, treatment regimes, and outcomes are discussed in detail.