Endoscopic Surgery for Sinonasal Cancer: Uludağ Experience

Abstract

Objective: The aim of this study is to evaluate the diagnosis and treatment results of patients who underwent endoscopic surgery in our clinic due to malignant paranasal sinus tumors.Material and Methods: Between January 2009 and December 2018, the files of patients with malignant paranasalsinus tumors, who were treated with endoscopic surgery only, without combining it with open surgery, were evaluated retrospectively. Demographic data, histopathological diagnosis, surgical characteristics, postoperative complications, and treatment results were determined.Results: A total of 15 patients, consisting of 7 males and 8 females, aged 17–84 years (average of 50.13) were includedin the study. The most common symptom was nasal obstruction, followed by epistaxis. Histopathologic diagnosiswas adenocarcinoma in 4 patients; olfactory neuroblastoma in 3 patients; hemangiopericytoma in 2 patients; andsquamous cell carcinoma, malignant melanoma, adenoid cystic carcinoma, sinonasal differencing carcinoma, andsmall cell carcinoma in the remaining patients. The diagnosis of malignant mesenchymal tumor and extramedullaryplasmacytoma was determined as two separate histopathologic diagnoses in 1 patient. The average follow-up periodwas determined as 33.3 months. Ten patients received postoperative adjuvant therapy, and 4 patients developedlocal recurrence.Conclusion: In patients with malignant paranasal sinus tumors, if negative surgical margins could be achieved withendoscopic surgery, endoscopic techniques have become more preferred today due to low morbidity rates. Successful oncologic results can be obtained with adjuvant therapies, even if there is a positive surgical margin withendoscopic surgeries.