Retrospective Analysis of Patients with Synchronous Primary Breast and Thyroid Carcinoma

Abstract

Objective: Breast and thyroid cancers are commonly encountered malignancies. Increased risk of breast cancer in follow-up period of thyroidcancer or vice versa has been reported. However, they have some associations, synchronous presentation of these tumors is rare. We presented 12patients diagnosed as breast and thyroid cancer and treated at the same time.Materials and Methods: Mastectomy and thyroidectomy were performed in 19 patients at the same time. 7 patients were excluded because ofbenign thyroid pathology. Therefore 12 patients who had diagnosis of synchronous breast and thyroid cancer were included. Data regarding clinical,pathological, treatment and prognostic factors was retrospectively analyzed.Results: Total thyroidectomy was performed in all patients. The mean age of patients was 54 years (min. 44- max. 70). Only one patient was male.Thyroid pathology was detected preoperatively by FDG PET-CT scan in 11 patients. Breast reconstruction was performed in three patients. Themost commonly seen thyroid malignancy was papillary thyroid carcinoma. Postoperative complication rate was 33.3%. Adjuvant chemotherapy wasgiven in 11 patients whereas one patient received adjuvant radiotherapy.Conclusion: Although synchronous presentation of breast and thyroid cancer is rare, surgical treatment of both of these tumors can be safely performedat the same time. Association of these tumors should be evaluated by large scaled studies.