Not Otherwise Specified-Type Sarcoma of Breast with CD10 Expression: Case Report

Abstract

Primary breast sarcomas are very rare and account less than 1% of invasive breast carcinomas. Primary sarcomas of breast are leiomyosarcoma, angiosarcoma, liposarcoma, firosarcoma, rhabdomyosarcoma, malignant peripheral nerve sheath tumor and pleomorphic sarcoma. Recently, a newCD10 positive group of sarcoma was identifid. Thse tumors cannot be classifid as a soft tissue sarcoma and show diffse strong positive stainingpattern with CD10 (NSCD10). Herein we report clinical and morphological characteristics of two cases diagnosed with not otherwise specifid-typesarcoma with CD10 expression by histologically and immunohistochemical fidings with the literature. NSCD10 shows similarity with leiomyosarcoma and sarcomatoid-type metaplastic carcinoma histomorphologically among specifi sarcomas of breast. CD10 expression should be taken intoconsideration in the presence of not diagnosed and not specifid tumors and CD10 should be added to the immunohistochemical panel.