Evaluation of Three-Dimensional Conformal Radiotherapyand Intensity Modulated Radiotherapy Techniques forLeft Breast Post-Mastectomy Patients: Our Experience inNigerian Sovereign Investment Authority-Lagos UniversityTeaching Hospital Cancer Center, South-West Nigeria

Abstract

Objective: This study aimed to evaluate the dosimetric properties of treatment plans obtained from three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy techniques (IMRT) plans for left chest wall breast cancer patients.Materials and Methods: A total of 20 patients with left-sided chest wall radiotherapy were randomly selected with the dose prescriptions: 42 Gy and 45 Gy in 15 and 18 fractions, respectively. Treatment plans were obtained using 3D-CRT and IMRT for each patient. Five to seven beams were used for IMRT, while tangential beams were used for 3D-CRT. Planning target volume, $D^{near-max}$ ($D^2$), $D^{near-min}$ ($D^{98}$), Dmean, Homogeneity and Conformity Indices (HI and CI) were obtained. Similarly, mean doses to organs at risk (OAR), $V^5$, $V^10$, $V^20$, $V^25$ were generated from the dose-volume histogram and compared.Results: IMRT showed a significant improvement in HI compared to 3D-CRT (p