Evaluation of the Effectiveness of Local Teicoplanin in Diabetic Tibia Plafond Fractures

Abstract

Objective: The aim of this study is to evaluate the effectiveness of local teicoplanin (TEC) administration in diabetic patients who underwent surgery for tibial plafond fracture.Methods: We retrospectively evaluated the records of 22 diabetic patients who underwent osteosynthesis with open reduction plate–screw fixation due to tibial plafond fractures between January2007 and January 2016. The cases were divided into two groups as teicoplanin group (Group T,n=12) and control group (Group C, n=10) based on perioperative administration of 400 mg TEC. Inaddition to demographic data, both groups were compared for the American Society of Anesthesiologists (ASA) score, duration of operation, length of hospital stay (LOS), post-surgical infection,and rates of reoperation and amputation.Results: There was no significant difference in preoperative demographic data and ASA scores between both groups. Although there was no significant difference between the two groups in termsof superficial wound infection, the rates of deep wound infection, reoperation, and LOS in GroupC were significantly higher than those in Group T.Conclusion: Perioperative local TEC administration in diabetic patients who underwent surgeryfor tibial plafond fracture seemed to be effective for deep wound infection, reoperation, and LOS.