Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Report

Abstract

Primary cutaneous anaplastic large cell lymphoma (PCALCL) is a rare cutaneous CD30 + T cell lymphoproliferative disorder. PCALCL usually presents as solitary andlocalized nodules and tumors, or may be multiple and ulcerated. Extracutaneous involvement may occur rarely. Systemic anaplastic large cell lymphoma with secondarycutaneous involvement has a similar clinical appearance to PCALCL, but differs in treatment and prognosis. Thus, systemic evaluation of patients considered as PCALCL iscritical. An 82-year-old male patient presented with three progressive lesions on the scalp. The final diagnosis was PCALCL with extracutaneous involvement based uponthe involvement of regional lymph nodes, liver and spleen, lack of systemic B symptoms and the results of histopathological and immunophenotypical studies. This caseis presented to emphasize the necessity of systemic evaluation in patients considered as PCALCL and to remind how to differentiate PCALCL from systemic lymphomas.