Relationship between hematological examination, glucose, ${mathrm{HbA}}_{1mathrm c}$ level, and disease stages in patients with obstructive sleep apnea syndrome

Abstract

OBJECTIVE: Obstructive sleep apnea syndrome (OSAS) is an episodic disease that is characterizedby intermittent partial interruption of breathing during sleep, which results in low oxygen levels inorgans and tissues. The characteristic symptoms of OSAS include snoring, apnea or hypopnea, andexcessive daytime sleepiness. Our aim is to determine the early diagnosis of diabetes and to initiatetreatments for OSAS patients according to the results of polysomnography (PSG) in the sleep polyclinicbased on fasting blood glucose and HbA1c levels in patients with known OSAS without diabetes.MATERIALS AND METHODS: Patients who applied to the sleep polyclinic of the PamukkaleUniversity and were diagnosed with OSAS using PSG were included in the study.RESULTS: A total of 44 patients with OSAS and a control group consisting of 47 people meetingthese criteria were included. Compared with the control group, the patient groups showed significantlyhigher Hb values (P 30) (r = −0.583, P = 0.02).CONCLUSION: In conclusion, even though significant differences were not found in the glucoseand HbA1c levels of patients with OSAS, glucose metabolism was deteriorated when saturation wasdecreased in severe OSAS. Therefore, glucose levels should be observed frequently, particularlyin severe cases of OSAS or in patients with hypoxia, regardless of the stage. More attention shouldalso be paid to the development of diabetes.