Characteristics of metachronous second primary lung cancers

Abstract

AIM: In this study, we aimed to investigate the characteristics of metachronous second primarylung cancer (MSPLC) and the differences between primary lung cancer (PLC) and metachronouslung cancer.MATERIALS AND METHODS: Patients diagnosed with lung cancer between January 2014 andDecember 2016 were retrospectively studied. MSPLC tumor cases and a new diagnosis of PLC wereevaluated. Clinical, radiological, and demographic findings of the two groups, previous histopathologicdiagnosis of MSPLC, histopathologic diagnosis of lung cancer in both groups, stages of treatment, andtreatment history were recorded. All data were analyzed using the Chi‑square, t‑test, Kaplan–Meier,and Log‑rank method. In all tests, P 0.05). The most frequent primary cancers were laryngeal carcinoma (11 cases)in the MSPLC group, with higher age (64 and 61, P = 0.01, respectively). Tumor size was smaller(44 mm and 52 mm, respectively) than the PLC group (P = 0.03). All other characteristics of bothgroups (P > 0.05) and survival were similar (15 months and 17 months, P = 0.87, respectively).CONCLUSION: Among the lung cancers diagnosed in our clinic, 16% were detected as MSPLC.MSPLC group were older than the PLC group and tumor size is lower than the PLC group. Therewas no significant difference in treatment options and survival between the two groups.