Reactions of nitrobenzo (c) cinnolines with hydroxylamine

Abstract

The reaction of 1-nitrobenzo[c]cinnoline with hydroxylamine in the presence of potassium hydroxide in ethanol gave the corresponding 2- and 4-amino derivatives. The reaction of 2-nitrobenzo[c]cinnoline 6-oxide with hydroxylamine under the same conditions yielded 2-nitrosobenzo[c]cinnoline 6-oxide. Mononitration of N-acetylbenzo[c]cinnolin-2amine occurred at position 1.