Kolo-rektal kanserli hastalarda lipid profili

Cafer POLAT, Müfide Nuran AKÇAY, Durkaya ÖREN, İrfan ALTUNTAŞ, Ali KILIÇ, Önder ÖZCAN

Özet

Kolo-rektal kanserde lipid profilini incelemek amacıyla, 46 kolo-rektal kanserli hastada ve 46 sağlıklı kontrol vakasında serum kolesterol, trigliserid, apolipopropein A-l ve apolipopropein B, yüksek-dansiteli lipoprotein kolesterol, düşük-dansiteli lipoprotein kolesterol ve çok düşük-dansiteli lipoprotein kolesterol düzeyleri incelendi. Hasta grubuna ait serum total kolesterol seviyesi kontrol grubundakinden düşüktü, ancak farklılık istatistiksel olarak anlamlı değildi (p>0.05). Benzer şekilde her iki gruptaki serum apolipopropein A-l ve B seviyeleri arasında da farklılık yoktu. Hasta grubundaki serum trigliserid (p

Abstract

İn order to investigate lipid profile in colorectal cancer, this study was conducted in 46 patients with colorectal cancer-and in 46 healthy control subjects. Serum cholesterol, triglyceride, apolipopropein A-l and apolipopropein B, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and very low-density lipoprotein cholesterol levels were quantified in the patient and control group. Serum total cholesterol level obtained in the patient group was lower than that of the control group, but the difference was not statistically significant (p>().()5). Like this, serum apolipoprotein A-l anıl B concentrations obtained in the patient group were not different from those of the control group. Serum triglyceride (p< 0.0001) and very low-density lipoprotein cholesterol (p