THE LEPTIN LEVELS OF OBESE AND NORMAL WEIGHT ADOLESCENTS WITH HEALTHY GINGIVA AND GINGIVITIS: EFFECTS OF PERIODONTAL THERAPY ON THE PARAMETERS

Abstract

Aim:The purpose of our study was to assess the role of leptin, a hormone secreted by adipose tissue, in the association of obesity and periodontal disease.Material and Methods:Fifty-six adolescents volunteered to participate in this study. The participants were divided into two groups (obese / normal) and each group was then divided into two subgroups (gingivitis /healthy gingiva). All of the adolescents were measured for clinical indexes such as plaque index (PI) and gingival index (GI). Levels of leptin in the gingival crevicular fluid (GCF) samples and serum leptin levels were determined in blood samples by enzyme linked immune sorbent assay (ELISA). Results: Blood leptin concentration (BLC) was higher in obese subjects than normal weight subjects (p