Dergiler / Archives of Basic and Clinical Research / 2021 / Cilt: 3 - Sayı: 2
Premenopozal Kadınlarda Tekrarlayan İdrar Yolu İnfeksiyonları ve Vitamin D Düzeyi Arasındaki İlişki
- Sayfa
- 59–64
- DOI
- —
Özet
Amaç: Bu çalışmamızda vitamin D eksikliğinin premenopozal kadınlarda tekrarlayan idrar yolu enfeksiyonları (İYE) üzerindeki etkisini incelemeyi amaçladık. Gereç ve Yöntemler: Çalışmada vaka grubu (tekrarlayan İYE olan 59 premenopozal kadın) ve control grubu (yaş uyumlu tek- rarlayan İYE olmayan 59 premenopozal kadın) çeşitli faktörler açısından karşılaştırıldı. Serum 25-hidroksivitamin D düzeyi (25(OH)D)
Abstract
Objective: This study aimed to determine the effect of vita- min D deficiency on recurrent urinary tract infections (UTIs) in premenopausal women. Materials and Methods: We conducted this study with the case group consisting of premenopausal women with recur- rent UTIs (n=59) and the control group consisting of age- matched premenopausal women without recurrent UTIs (n=59). Vitamin D deficiency was diagnosed when 25-hy- droxyvitamin D (25(OH)D) level was less than 20 ng/mL, and a serum 25(OH)D level of above or equal to 20 ng/mL was ac- cepted as normal. Results: The mean age of patients in the case group and the control group was 32.22 ± 5.26 years and 31.78 ± 5.60 years, respectively (p=0.661). The mean value of 25(OH)D level was 18.97 ± 6.91 ng/mL in the case group and 22.27 ± 5.21 ng/mL in the control group. A statistically significant difference was found in terms of marital status (p=0.015) and serum 25(OH) D levels (p=0.004) between the two groups. Independent risk factors for recurrent UTIs were analyzed by a logistic regres- sion analysis. Marital status (p=0.028) and vitamin D deficien- cy (p=0.015) were independently associated with recurrent UTIs in premenopausal women. Conclusion: We found a significant relationship between recurrent UTIs and vitamin D deficiency in premenopausal women.