Anterior segment parameters and tear functions in patients with thalassemia major

Abstract

Aim: To determine whether the biomicroscopic, topographic and biomechanical properties of the anterior segment and the tearfunction have changed in Thalassemia Major (TM) patients.Material and Methods: Eighty-eight eyes of patients with TM and 102 eyes of healthy controls paired with age, gender, and sphericalequivalent were included in this cross- sectional case-control study. Biomicroscopic, topographic and biomechanical findings ofanterior segment and Schirmer test measurements were compared between the two groups.Results: The mean age was found to be 15.11±6.01years in TM group, and 13.83±4.92 years in the control group (p=0.17). In 34(38.63%) patients with TM, minor peripheral lens opacities were detected. Visual acuity was 20/20 in all patients with lens opacity.The mean iridocorneal angle (ICA) was 44.67±5.86 and the topographic anterior chamber depth (ACD) was 3.65±0.28 mm in the TMpatients. Mean ICA was 48.78 ± 6.51 and topographic ACD was 3.76±0.30 mm in the control group (p