The impact of bariatric surgery on hematological inflammatory parameters

Abstract

Aim: The aim of this study was to evaluate hematological inflammatory parameters before and after bariatric surgery and investigatethe effect of surgery on these parameters.Material and Methods: A total of 71 patients who underwent a Roux-en-Y gastric bypass (RYGBP) or a sleeve gastrectomy (SG)procedure were included in the study. The preoperative levels of the inflammatory parameters of C-reactive protein (CRP) and thewhite blood cell count (WBC), as well as the hematological inflammatory parameters of red blood cell distribution width (RDW),mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), and the neutrophil-to-lymphocyte ratio (NLR) werecompared with the postoperative 6th and 12th month values.Results: Both the RYGBP and SG surgical techniques were used in this study. Significant reductions were seen in the postoperative6th and 12th month values of CRP and WBC, which were used as an indicator of the severity of inflammation. Along with the decreasein BMI and the standard indicators of inflammation, there were also corresponding statistically significant changes in the levels ofthe more recently used hematological inflammatory markers of RDW, MPV, PDW, PCT, and NLR (p