Evaluation of specific heavy metal levels of pregnant women complicated by neural tube defects

Abstract

Aim: The etiology of neural tube defect (NTD) is still not clear enough. In our study, we aimed to evaluate plasma heavy metal levelsof pregnant women with NTD and to determine whether there is a relationship between heavy metal levels and NTD severity.Material and Methods: TThis study was conducted in Adıyaman University, Department of Gynaecology and Obstetrics. The studyincluded 38 pregnant women with NTD and 42 pregnant women with healthy infants. Pregnant women who have NTD were dividedinto two groups as NTD Type 1 and NTD Type 2 according to the anomaly type. Levels of heavy metals such as Mercury (Hg),Cadmium (Cd), Cobalt (Co), Lead (Pb), Manganese (Mn) and Arsenic (As) were compared between groups.Results: Plasma Hg, Co, Cd and Pb levels were higher in NTD group than control group. (p values, respectively; p