Association between serum 25-hydroxyvitamin d and early recurrent ischemic stroke

Abstract

Aim: Vitamin D deficiency has been reported as a new risk factor for ischemic stroke in recent years. However, the pathophysiologicalmechanisms between recurrent ischemic stroke and decreased 25-hydroxyvitamin D [25(OH) D] are not clear. The aim of this studyis to examine the relationship between initial vitamin D levels and early recurrent stroke in patients presenting with acute ischemicstroke (AIS).Material and Methods: Four hundreds and ten consecutive patients who were followed-up with AIS diagnosis were included in thestudy. Risk factors for ischemic stroke were questioned and biochemical and cardiac examinations of the patients were performed.Simultaneously, the National Institutes of Health Stroke Scale (NIHSS) was calculated. Patients who had recurrent ischemic strokeobtained retrospectively were from the hospital registry system in last three month. The patients were divided into two groups asthose who had recurrent stroke and who did not.Results: A total of 410 patients, 187 of which were female (45.6%) and 223 of which were male (54.4%) with a mean age of 68.12 ±12.63 (29-99) were included in the study. Early recurrent ischemic stroke was detected in 48 (11.7%) patients in the follow-up. Thesystolic blood pressure and diastolic blood pressures at the time of first consultation were higher in the recurrent ischemic strokegroup compared to the non-recurrent ischemic stroke group (p