Clinical features associated with convulsive status epilepticus in patients with epilepsy

Abstract

Aim: Status epilepticus (SE) is an important and distinct problem with its high morbidity and mortality. The need for early identificationof SE to predict the course and prognosis of epilepsy have led us to investigate the clinical features associated with SE in patientswith epilepsy in this study.Material and Methods: The information of the patients with epilepsy recorded comprised demographic features, type and etiology ofseizures, age of onset of epilepsy, frequency of seizures, mono- or polytherapy treatment, history of convulsive SE, triggering factorsfor SE and brain magnetic resonance imaging findings. The data also included patients’ family history of epilepsy and history offebrile seizures, mental retardation.Results: A total of 610 patients with epilepsy (291 men, 319 women) were included in the study. It was found that 49 (8%) of thepatients had at least one convulsive SE. Univariate logistic regression analysis showed that earlier onset of epilepsy, symptomatic/cryptogenic etiology, mental retardation, frequency of seizures ≥1/month, treatment with polytherapy, and abnormalities inneuroimaging are associated with SE (p=0.001, p