Comparison of young and elderly patients with rectal cancer in terms of prognostic factors and clinical features: A retrospective analysis

Abstract

Aim: Rectal Carsinoma (RC) has considerable morbidity, mortality, and highly operational costs. RC is generally known as a diseaseof the elderly especially beyond the age of 50 years. Nevertheless, the incidence of RC in younger adults (aged ≤50 years) has beenincreasing widely. Our aim is to evaluate the clinical and histopathological features of the patients under and over 50 years with RCand their contribution to prognosis.Material and Methods: Patients with RC who were treated in our clinic included in the current retrospective designed study, andtheir data collected including demographics, clinical presentations, histopathological features, disease characteristics, treatmentreceived or not, survival and outcomes. Their variables were compared statistically.Results: This study included 187 RC patients from our General Surgery Clinic. Median age at diagnosis was 62 years (min:26-max:88). Lack of perineural invasion significantly affected disease-free survival and overall survival in general (p