The role of Diffusion-weighted magnetic resonanceimaging and apparent diffusion coefficient (ADC) values inthe evaluation of solid breast lesions

Abstract

Aim: To investigate the role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values inthe differential diagnosis of solid lesions of the breast.Materials and Methods: Diffusion-weighted images and ADC values from 36 women with 37 solid lesions definitely diagnosedthrough breast biopsy and post-surgical histopathology were evaluated retrospectively. ADC values obtained from malignant andbenign solid lesions of the breast were compared using the t-test. The optimum threshold value for use in differentiating benign andmalignant lesions was determined using ROC analysis, and sensitivity and specificity values were calculated. Results: Histological analysis identified 23 lesions and 14 benign lesions. Mean age (49 ± 7.8 years) was higher in the group withmalignant breast lesions than in the group with benign breast lesions (37.3 ± 8.2) (p