Role of Renal Resistive Index in Predicting the Severity of Coronary Artery Disease in Patients with Mild to Moderate Renal Insufficiency

Renal Resistive İndeks'in Hafif Orta Böbrek Yetersizliği Olan Koroner Arter Hastalarında Hastalık Şiddetini Belirlemedeki Yeri

Özet

Amaç: Çalışmamızda hafif orta renal yetersizliği olan hastalarda renal resistive indeksini (RRİ)saptayarak bunun renal fonksiyonlar ve koroner arter hastalığının (KAH) şiddetiyle ilişkisini araştırdık. Materyal ve Metot: Çalışmaya koroner angiografisi yapılarak KAH tanısı konmuş 41 erkek,35 kadın toplam 76 hasta alındı. Tüm hastalarda renal doppler ultrasonografi (US) ile RRİ' leri ölçüldü. Renal parankim kalınlığı, böbrek uzunluk ve genişlikleri ölçüldü. Gensini risk skorlama sistemiyle KAH şiddeti skorlanarak hastalar hafif-KAH (Gensini skoru 20) olmak üzere iki guruba ayrılarak karşılaştırıldı. Ayrıca tüm hastalarda glomerular filtrasyon hızı (eGFR) hesaplanarak 3 ayrı sub gruba ayrıldı ve RRI ile ilişkisi araştırıldı. Bulgular: Gensini skoruna göre şiddetli KAH olanlarda hafif KAH olanlara göre anlamlı derecede yüksek RRİ değerleri saptandı [0,62 (0,58-0,71)] karşı [0,71 (0,63-0,78)], p =90) olanlarda RI [0,63(0,59-0,68)], evre 2 olanlarda RI [0,77(0,71-0,84)],evre 3 olanlarda ise RI [0,81(0,73-0,85)]idi, (p

Abstract

Objectives: The aim of this study was to determine the renal resistive index (RRI) in patients with mild to moderate renal insufficiency, and to investigate the relationship between RRI and the severity of coronary artery disease (CAD) and renal function. Materials and Methods: The study included 76 patients diagnosed with CAD on coronary angiography. The patients comprised 41 males and 35 females. Renal resistive index was determined using renal Doppler ultrasonography (RDU). Renal length, width, and parenchymal thickness was measured. The severity of CAD was graded according to Gensini score, and the patients were divided into two groups: mild atherosclerosis (Gensini score =20 points). The estimated glomerular filtration rate (eGFR) was calculated for each patient. Based on GFR stage, the patients were divided into three groups, and the relationship between RRI and GFR stage was investigated. Results: Gensini scores indicated that the RRI was significantly higher in the patients with severe CAD compared to those with mild CAD [0.62 (0.58-0.71)] vs. [0.71 (0.63-0.78)], p= 90), was [0.77(0.71-0.84)]in patients with stage 2 (GFR 60-89) and was [0.81(0.73-0.85)]in patients with stage 3 (GFR 30-59) (p