Sol ventrikül hipertrofisi hipertansif hastalarda ventriküler aritmi sıklığını arttırıyor

Left ventricular hipertrophy increases the frequency of ventricular arrhythmia in hypertensive patients

Turgut KARABAĞ, Ahmet TEMİZHAN, Kurtuluş ÖZDEMİR, Ayşe ÖZDEMİR, Bülent B. ALTUNKESER, Mete ALPASLAN, Hasan Hüseyin TELLİ

Özet

Amaç: Hipertansif hastalarda sol ventrikül hipertrofisi (SVH) ve sol ventrikül geometrik yapısı ile aritmi riski ve QT dispersiyonu (QTd) arasındaki ilişkiyi araştırmak. Yöntem: Çalışmaya 80 hasta alındı (ortalama yaş 53 ± 11 yıl, 45'i kadın). Konsantrik SVH 30, konsantrik remodeling (KR) 15 ve normal sol ventrikül geometrisi (NG) 35 hastada tespit edildi. Hastalara 24 saatlik elektrokardiyografik monitorizasyon yapıldı, QTd ölçüldü. Bulgular: Otuz hastada (%37) Lown 2 ve üzeri ventriküler aritmi, 17 hastada (%21) ise Lown evre 4a ve 4b ventriküler aritmi saptandı. Konsantrik hipertrofili hasta grubundaki ventriküler aritmi (Lown 2 ve üzeri) normal geometrili ve konsantrik remodelingli hasta gruplarına göre istatistiksel olarak anlamlı düzeyde yüksek bulundu (p

Abstract

Objective: To evaluate the relationship between left ventricular hypertrophy (LVH) and geometrical structure of the left ventricle with the risk of arrhythmia and QT dispersion (QTd) in hypertensive patients. Methods: Eighty patients were included (mean age 53 ± 11 years, 45 women,) in the study. Among them, concentric LVH was present in 30, concentric remodelling in 15 and normal left ventricular geometry in 35 patients. Twenty-four hours electrocardiographic monitoring and QTd calculation were performed for all patients. Results: Lown grade 2-3 ventricular arrhythmia was found in 30 patients (%37) and Lown grade 4a-4b ventricular arrhythmia was documented in 17 patients (%21). The frequency of > Lown 2 ventricular arrhythmia in patients with concentric LVH was significantly higher than those of the subjects with concentric remodelling or normal geometry (p Lown 2 ventricular arrhythmias were %80 in patients with LVH and %10 in patients without LVH. QT and QTc dispersions in patients with concentric hypertrophy were significantly longer than those of the patients with concentric remodelling and normal geometry. Additionally, QT and QTc dispersions in patients with ventricular arrhythmias were more frequent than in those without (p