Relationship between umbilical artery Doppler indices and adverse pregnancy outcomes in women with insulin-dependent diabetes mellitus

Abstract

Objective: It is intended to research the value of umbilical artery (UA) and middle cerebral artery (MCA) Doppler indices in predicting adverse pregnancy outcomes in women with insulin-dependent diabetes mellitus. Material and Methods: The study was planned at Zeynep Kamil Women and Chil- dren’s Diseases Training and Research Hospital. Pregnant women were divided into two groups: group 1 consisted of 123 fetuses with normal pregnancy outcomes and group 2 had 74 fetuses with adverse pregnancy outcomes. The value of the UA sys- tole/diastole (S/D) ratio was questioned to predict possible adverse pregnancy out- comes. Differences in Doppler measurements between the groups with p<0.05 were considered statistically significant. Results: UA S/D ratios were established as ultrasonographical parameters in pre- dicting normal pregnancy outcomes at 28th , 32 nd , and 36th weeks of gestation, with cutoff values of 2.58, 2.56, and 2.62, respectively. Negative predictive values of these three cutoffs for adverse pregnancy outcomes were 70.21%, 72.53%, and 69.03%, respectively. Conclusion: UA S/D ratios may be helpful to the clinic as ultrasonographical mea- surements to predict the normal pregnancy outcomes at 28 th , 32 nd , and 36 th weeks of gestation.