Polyarteritis nodosa in case of familial Mediterranean fever

Özet

Familial Mediterranean fever (FMF) is an autosomal recessive diseasecharacterized by recurrent self-limited attacks of fever accompanied byperitonitis, pleuritis, and arthritis. Protracted febrile myalgia syndrome(PFMS) is a rare form of vasculitic disease which is an uncommon dramaticmanifestation of FMF, characterized by severe crippling myalgia and highfever. Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affectingmedium or small arteries. It is rarely observed in children, but its incidenceincreases in the presence of FMF. In this article we described a 14-year-oldchild diagnosed with FMF associated with PAN. Physicians should be awareof this possible association.