Two cases of Wegener's granulomatosis with pancreatic pseudocyst treated by endoscopic ultrasonography (EUS)-guided drainage

Endoskopik ultrasound ile tanı alan 2 adet Wegener granülomatozlu pankreatik psödokist vakası

Özet

Wegener granülomatozu sistemik bir vaskülit eşidi olup respiratuar sistem ve böbrek tutulumu belirgindir. Literatüde 10 adet pankreatit tanısı alan Wegener granülomatozlu vaka mevcuttur. Yazımızda 2 adet akut pankreatitle birlikte psödokist geliştiren vakayı bildiriyoruz. Pankreatik psödokistlerin endoskopik ultrasonografi ile drenajı çabuk klinik iyileşme sağlamaktadır. Pankreatik psödokist Wegener granülomatozu hastalarında sık olarak bildirilmemiş olup mevcut vakalar ilk örneklerdir. Bu yöntemin güvenirliliği yazımızda tartışılmıştır

Abstract

Wegener's granulomatosis is a systemic vasculitis with prominent involvement of the respiratory tract and kidney. There are 10 patients with Wegener's granulomatosis in the literature who were documented as acute pancreatitis. We present two cases with Wegener's granulomatosis presenting with acute pancreatitis and pancreatic pseudocyst. Endosonography-guided drainage of the pancreatic pseudocyst led to rapid clinical improvement. Pancreatic pseudocyst in Wegener's granulomatosis is not reported in the literature, and these are the first cases of Wegener's granulomatosis to be managed by endosonography-guided cyst drainage. The safety of endosonography-guided pancreatic pseudocyst drainage and the clinical features of the previous Wegener's granulomatosis cases with acute pancreatitis are discussed.