Kounis syndrome associated with BNT162b2 mRNA COVID-19 vaccine presenting as ST-elevation acute myocardial infarction

Özet

Vaccination is considered the key process of immunization against the ongoing pandemic. The mass vaccination process has started with different vaccine types, varying globally. Because of the accelerating vaccination efforts worldwide, the possibility of rare adverse effects happening has increased. Over 100 million COVID-19 vaccine doses has been administrated in Turkey (1). Although it is known that the adverse effects of COVID-19 vaccines have low incidence (2), allergic side effects are possible similar to any other medication. Although a wide spectrum of symptoms can be seen, from mild allergic complaints to angioedema, Kounis syndrome is one with undesirable effects. Hypersensitivity coronary disorder was originally described in 1991 by Kounis as acute coronary syndrome associated with an allergic reaction (3). This syndrome has been reported with different SARS-CoV-2 vaccines (4, 5); and to the best of our knowledge, we present the first Kounis syndrome after an mRNA vaccine.