Neuroanatomical Aspects of the Temporo–Parieto– Occipital Junction and New Surgical Strategy to Preserve the Associated Tracts in Junctional Lesion Surgery: Fiber Separation Technique

Özet

AIM: To describe the location of each white matter pathways around the temporo–parieto–occipital junction (TPOJ) and thedissections performed using focal fiber dissection and fiber separation techniques (FST). These areas play an important role inhuman language processing and high-level brain functions. Thus, it is important to identify the association of the fascicles as wellas their courses to plan safe and effective surgical target vectors.MATERIAL and METHODS: Thirty formalin-fixed human hemispheres and two formalin-fixed human heads were dissected withfocal fiber dissection and FST under 6–40× magnification using a surgical microscope and real-time magnetic resonance imagingnavigation system. Two- and three-dimensional anatomical and surgical pictures were obtained and processed using high dynamicrange photography (Photomatix) and were correlated to radiological images of the case with glioblastoma of the TPOJ.RESULTS: The trajectory and connectivity of these fibers as well as their surgical importance in performing FST in cadaverdissections were demonstrated with correlation of the surgical, radiological, and anatomical images.CONCLUSION: The microanatomy of the TPOJ and related structures, emphasizing the position of each white matter pathway, hasbeen described. Understanding the composition of each region is critical in preventing intraoperative brain injury that could lead tofunctional deficits.