Correlation of Preoperative Radiological Evaluation of Skull Base and Non-skull Base Meningiomas with Clinical and Surgical Data

Özet

AIM: To determine whether neuroradiological assessment of skull base and non-skull base meningioma consistency and vascularitycan be used to improve the surgical approach.MATERIAL and METHODS: Forty meningioma cases were split into skull base (n=16) and non-skull (n=24) base groups, andintraoperative surgical reports of observed tumor consistency (stiffness) and vascularity were compared with preoperativeneuroradiological magnetic resonance (MR) perfusion and postoperative histopathological analysis of collagen and CD34 levels.RESULTS: The skull base group had significantly higher CD34 levels (p=0.004) than the non-skull base group. Further comparisonof CD34 levels also revealed significantly higher CD34 levels (p=0.032) in transitional versus fibroblastic subtypes. Observationbased vascularity scoring did not reveal a significant correlation between tumor grade and relative cerebral blood volume (p=0.604).In contrast, there was a statistically modest, but significant correlation between intraoperative observation-based consistency andVerhoeff-van Gieson collagen scores (rs=0.400).CONCLUSION: Preoperative assessment of consistency and vascularity using MR imaging was ambiguous. Overall, one of themost important limiting factors was the subjective observational assessment of tumor consistency and vascularity by surgicalteams.