Inflammatory Events in Patients with Sagittal Imbalance through Platelet-Associated Inflammation

Özet

AIM: To determine whether platelet-associated inflammation parameters (PAIP) could be useful for evaluating inflammation insagittal imbalance (SI) by investigating its relationship with pelvic tilt (PT), sacral slope (SS), pelvic incidence (PI), lumbar lordosis(LL) and thoracic kyphosis (TK).MATERIAL and METHODS: The study included 57 patients (19 males, 38 females) who were diagnosed with SI and 44 healthycontrol subjects. Spinal sagittal balance was evaluated using digitalized-standing lumbar lateral radiographs of the patients. Allparameters including SS, PI, LL and PT were evaluated through from the lateral radiographs.RESULTS: In the analysis, Mean Platelet Volume (MPV) (10.6 ± 0.9; p 0.05). The PT had a positive correlation with hospital length of stay in SI patients (r=0.655;p=0.008). MPV showed a strong positive correlation with comorbidity (r=0.715; p=0.001). A positive correlation was determinedbetween NLR and PLR (r=0.692; p=0.002), and between MPV and RDW (r=0.788; p=0.001). No correlation was determined betweenthe PAIP and radiological measurements (PI, PT, SS) that were used for SI.CONCLUSION: The results suggest that the neurosurgical approach should cover not only the sagittal parameters and their anglesbut also PAIP showing inflammatory events originating from platelets.