Comparison of Thalamus Volume on Magnetic Resonance and Cadaveric Section Images

Özet

AIM: To measure and to compare the volume of thalamus using magnetic resonance imaging (MRI) and the anatomical sections.MATERIAL and METHODS: In this study, 13 brain specimens were used. First, the images were taken in 3 mm sections on MRI,the thickness of the thalamus was measured. Subsequently, 4 mm coronal sections were prepared using a microtome. The thalamicvolumes calculated from cadaveric specimens were compared with the measurements obtained using MRI.RESULTS: On MRI, the mean thalamic volumes on the right and left hemispheres were found to be 5843.4 ± 361.6 mm3 and 5377.0± 666.2 mm3 respectively. The mean volumes of the cadaveric sections were 5610.8 ± 401.3 mm3 on the right side and 5618.5 ±604.1 mm3 on the left hemisphere. No statistically significant difference was found between the volume calculated from MRI andthat obtained from the cadaveric section (p<0.05).CONCLUSION: This study shows a correlation between measurement of thalamus volume based on MRI and those calculated fromanatomical sections. Our findings support the reliability of DBS procedures using MRI and stereotactic method.KEYWORDS: Cadaver, Deep brain stimulation, Magnetic Resonance Imaging, Planimetry technique, Thalamus