The Incidence of Glaucoma Following Deep Anterior Lamellar Keratoplasty and Penetrating Keratoplasty

Özet

Objective: To evaluate the incidence of glaucoma and the response rates to anti-glaucoma treatment after deep anterior lamellar keratoplasty (DALK) in comparison with penetrating keratoplasty (PK). Methods: In this retrospective study, 146 patients with DALK and 156 patients with PK were evaluated. All patients were followed up on the 1 st , 3 rd , 6 th , 12 th and 24 th days after the keratoplasty procedure. The risk factors and incidence of glaucoma and glaucoma treat- ments were assessed in both the DALK and the PK groups. Results: A total of 156 eyes with DALK procedure and 163 eyes with PK procedure were included. Eleven eyes in the DALK group (7.05%) and 16 eyes in the PK group (9.81%) were diagnosed with glaucoma (p=0. 42). The median number of anti-glaucoma drugs was 1.0 in DALK groups and 1.5 in PK groups (p=0.01). Trabeculectomy with mitomycin C was per - formed in 4 of the 16 eyes (25%) with glaucoma after the PK (p=0.01). In the DALK group, patients were followed up with mono anti-glaucoma treatment therapy without surgical intervention. Conclusion: In our study group, the incidence of glaucoma was 7% in eyes with DALK and 9.8% in eyes with PK. However, the number of glaucoma drugs was significantly high- er in eyes with PK procedure than eyes with DALK procedure (p=0.01). Moreover, eyes with DALK have needed less trabeculectomy with mitomycin C compared to eyes with PK. Therefore; our results suggested that the DALK procedure might be more appropriate and safer than PK concerning glaucoma development